And I will smite the inhabitants of this city
With one or other of his arrows after mentioned: or, "them that abide in this city" {o}; that do not go out of it, and surrender themselves to the king of Babylon; see ( Jeremiah 21:9 ) ; both man and beast;
the latter for the sin of the former; particularly such beasts as were fit for food are meant, whereby the famine would be increased, and so the greater destruction of men: they shall die of a great pestilence;
both man and beast; a disease which comes immediately from the hand of God; hence Hippocrates used to call it (to yeion) , "the divine disease": here it denotes a very uncommon one, which should sweep away large numbers; called great, both for quality, or the nature of it, and for the quantity of persons that died of it.