Genesis 50:23

And Joseph saw Ephraim's children of the third generation,
&c.] His great grandchildren's children; and which shows, as most interpreters observe, that Jacob's prediction, that Ephraim should be the greatest and most numerous, very early began to take place:

and the children also of Machir, the son of Manasseh, were brought up
upon Joseph's knees;
Machir had but one son by his first wife, whose name was Gilead; but marrying a second wife, he had two sons, Peresh and Sheresh; see ( 1 Chronicles 7:14-16 ) who might be born before the death of Joseph, and be said to be brought up upon his knees, being educated by him, and often took up in his lap, and dandled on his knees, as grandfathers, being fond of their grandchildren, are apt to do.