He shall die without instruction
Into the evil of sin, and the danger he is in, and so without repentance for it; for instruction is the means of repentance, and productive of it when blessed, ( Jeremiah 31:19 ) ; but it is but just that those who have hated and rejected it in health and life, that when they come to die should have none given them about the evil of sin, the danger of their state, and the way of salvation; or rather "because of instruction" F26; because they would not bear and receive, but neglected, rejected, and despised it, so Aben Ezra and Ben Gersom; or "without correction" F1, or discipline and amendment by it; and in the greatness of his folly he shall go astray;
being left to the exceeding great folly of his mind, he shall continue to go astray as he has done from God and his good ways, from the precepts of his law, and the rules of his word; going after his own heart's lusts, which will drown him in perdition. This "folly" may be understood either of his fornication and adultery, which is egregious folly; or of his imagining that he should be able to repent of sin when he pleased, and free himself from the bondage of it, and escape the punishment due unto it.