And they shall drink, and be moved, and be mad
The judgments foretold shall come upon them, whether they will or not; which will have such effects upon them, as intoxicating liquor has on drunken persons; make them shake and tremble, and reel to and fro, and toss and tumble about, and behave like madmen: because of the sword that I will send among them;
this explains what is meant by the wine cup of fury, the sword of a foreign enemy that shall enter among them and destroy; and which would make them tremble, and be at their wits' end, like drunken and mad men.